Pakistan's Babar Azam and Shan Masood opened a 205-run partnership to keep the second Test against South Africa alive.
The visitors were forced to follow on at Newlands after being bowled out for 194 on day three.
In response to South Africa's first innings total of 615, Masood (102 not out) crossed three figures late in the day, while Azam was dismissed on 81 before Marco Janssen closed.
Pakistan started the day on a 64-3 lead, trailing South Africa by 314 runs, with the hosts still in contention for the second time.
Former Test captain Azam made 58 before being dismissed by Koena Mafaka to end his 98-run partnership with wicket-keeper Mohamed Rizwan (46).
Azam's departure started a run of wickets for Pakistan, as the visitors lost their last seven matches by 76 runs.
Kagiso Rabada took three wickets, with spinners Keshav Maharaj and Maphaka taking two each.
With Pakistan trailing by 421 runs, South Africa forced the follow-on only to see Rizwan and Azam register Pakistan's highest opening partnership since December 2022.
The tourists still face an uphill task, needing 208 more runs to draw with South Africa, with two days of action remaining.
The Proteas are playing in their final Test match before facing Australia in the World Test Championship final at Lord's in June.
Australia booked its place in the final on Sunday. Winning the final Test against India in Sydney to seal a 3-1 win.